Read on to learn about the methods, benefits, risks and implications of using or misusing fentanyl. Log in or create an account for a personalized experience based on your selected interests. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Duplication for commercial use must be authorized by ASHP. Be sure to schedule appointments with your doctor on a regular basis so that you do not run out of medication. Call your doctor if you have any unusual problems while using this medication.
If Fentanyl Is So Deadly, Why Do Drug Dealers Use It To Lace Illicit Drugs?
Because fentanyl is so potent and commonly found in the drug supply, it is easy for people to accidentally overdose on fentanyl. A fentanyl overdose can occur after the drug is injected, swallowed, snorted, or smoked. Symptoms of a fentanyl overdose, including slow or absent breathing, generally occur within minutes of the overdose. Death can follow quickly if the overdosed person isn’t treated.
Anyone can purchase Narcan over the counter, and there are places that give it away for free (see below). In recent years the drug supply has become overrun with illicitly manufactured synthetic fentanyl, which can be manufactured very cheaply. The fentanyl we see in the US drug supply mostly comes from Mexico and China. Fentanyl test strips can identify the presence of fentanyl in unregulated drugs.
- The information on this site is for educational purposes only, and does not substitute for professional medical advice.
- As with other opioid drugs, fentanyl binds to the receptors in the brain that affect pain and emotion.
- That is, in combination with certain neuroleptic medications as part of therapeutic neuroleptanalgesia.
- His brother reported that the boy had taken a blue tablet labeled “M30,” which the boy believed to be oxycodone.
- While some urine drug screens can detect fentanyl, others do not.
General Health
Typically, a fentanyl overdose manifests as an extrapolation of its pharmacological side effects. Although the clinical scenarios may vary among patients, one of the main concerns is the level of expression of OIRD. In such cases, oxygen administration and respiratory assistance are a priority.
From May 2020 to April 2021, more than 100,000 Americans died from a drug overdose, with over 64 percent of these deaths due to synthetic opioids like fentanyl and its analogs. Fentanyl and other synthetic opioids have now surpassed heroin and prescription painkillers as the deadliest drugs in the United States. They killed more than 19,000 Americans in 2016, topping heroin (15,000) and prescription opioids (14,000) for the first time. The shadowy addition of fentanyl to the illegal drug supply sent deadly overdoses skyrocketing among users who were unaware they were using such a strong drug.
In An Emergency? Need Treatment?
As Vox’s German Lopez previously explained, fentanyl has been around since the 1960s, but its illicit use has spiked in recent years. It is relatively easy to produce and is much more potent than heroin. They have been working on this investigation since last year, and their full findings will be reviewed at a Senate hearing on Thursday. One of the deadliest street drugs, illicit fentanyl, has transitioned from a hidden killer that people often hope to avoid to one that many drug users now seek out on its own. According to law enforcement officers and former drug dealers interviewed by ABC News, drug dealers often think they can mitigate the risk for their clients by measuring the fentanyl carefully. “In order to buy the product, you have to use cryptocurrency, which requires a high level of technology,” she said.
Which Darknet Market Is Safe
Overdose prevention sites allow individuals to use previously acquired drugs in a safe and supervised space to prevent overdose fatalities (for more on OPS). Fentanyl is a synthetic opioid that is 50 to 100 times more potent than morphine. It is prescribed to treat severe pain but is also misused and a major contributor to the opioid crisis. In addition to receiving treatment for a substance use disorder, people who use illegal drugs can help prevent overdoses by using fentanyl test strips.
Harm Reduction Approaches
Her partner was pronounced dead, and his autopsy also showed fentanyl in his blood. There is no set amount that is considered lethal because how the drug affects you depends on several factors such as your body size and tolerance. As little as 2 milligrams or less may cause death, which is about the size of a few grains of salt. Fentanyl stays in your system and can be detected by a drug test for 24 to 72 hours.
- Sometimes, individuals mix it with other drugs because of its potency.
- Other strategies to prevent overdose deaths include lowering the entry barrier to addiction treatment, fentanyl test strips, supervised consumption sites and even prescription diamorphine (heroin).
- The medication in each product is absorbed differently by the body, so one product cannot be substituted for any other fentanyl product.
- While it’s safe for your doctor to give you fentanyl in a medical setting, some people abuse it, which can lead to an overdose.
- Despite the evidence supporting these measures, however, local politics and funding priorities often limit whether communities are able to give them a try.
Does NIDA Collect And Release The Data On This Webpage?

Bold strategies are needed to interrupt the ever-increasing number of fentanyl-related deaths. If you use opioids a lot, you may find that you develop a tolerance and need more and more to feel the same effects. You can become mentally and physically dependent on fentanyl.
Administration
Once you’ve been taking fentanyl for a while, your body gets used to it and stopping can be very hard. It can be hard to function without the drug in your system. Most people need help from a health professional or program to successfully quit. One line is a positive result and means there is fentanyl in your drug supply.
Older Black Men Are Disproportionately Affected By The Overdose Crisis

Many states have laws that protect not only the person who calls for help, but also the person overdosing from legal trouble. The U.S. Drug Enforcement Administration estimates more than 258,000 people died from fentanyl overdose between 2013 and 2021. Fentanyl acts like many other opioids such as morphine and heroin. Sometimes people freeze fentanyl patches and cut them into smaller portions. Then they put these small pieces in their cheeks or under their tongue.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.
There are two types of fentanyl – pharmaceutical fentanyl and illegally made fentanyl. From April 2024 to March 2025, the CDC reported 43,000 synthetic opioid deaths, most of which are from fentanyl, down from nearly 70,000 in the previous similar period. Alternatively, some people may take illegally manufactured fentanyl for its heroin-like effect. Sometimes, individuals mix it with other drugs because of its potency.