People sometimes take illegally made fentanyl knowingly, either by itself or with other drugs in various forms, such as powders or pills. People can also unknowingly consume fentanyl when it is mixed into or sold as other drugs, including heroin, cocaine, or counterfeit pills. Initial reports of fentanyl abuse were linked to prescription products, but in recent years, illicit fentanyl has become the most commonly abused form.
Synthetic opioids sold illicitly can be mixed with heroin or cocaine, which amplifies its potency and potential danger. This is particularly dangerous if an individual who uses illegal substances like heroin or intentionally misuses prescription drugs is unaware that fentanyl could be in it. Darknet markets are online marketplaces located within the dark web that rely on cryptocurrencies (e.g., Bitcoin, Monero) and advanced encryption techniques to ensure the anonymity of buyers and sellers (Barratt and Aldridge, 2016). Due to the nature of darknet markets, the exact share of the drugs supplied by these markets remain unknown. With over 60 % of listings offering psychoactive substances (Europol, 2017), darknet markets offer the possibility to collect timely non-routine type of data to complement more traditional data sources (Singleton et al., 2018). The average price of a gram of non-pharmaceutical fentanyl was U.S.$1,470.4 for listings offering less than 5 grams and U.S.$139.5 for listings offering 5 grams or more.
Why Do People Take Fentanyl?
We present a view about how such services operate and how different entities interact with each other (Figure 1). The market dynamic of import and local production is of particular interest for legislation and prosecution. A trend towards ultrapotent opioids would generally mean that less total amount of substance is needed to be smuggled across the border. Darknet markets are online platforms that operate on encrypted networks, allowing users to buy and sell a variety of illicit goods and services anonymously. These markets are accessed using special software that enables users to browse and make purchases without revealing their identities.
Deaths Involving Illegally Made Fentanyl Are Rising
And he actually claimed to be doing some good in the world, if you can believe that. He was selling a nasal spray with a type of fentanyl and it was very cheap. And, despite the fact that he was selling this type of fentanyl over the dark Web, his contention was that he was helping addicted users like himself maintain their addiction affordably. To understand how it works, we describe an opioid transaction’s operational steps on the anonymous online marketplaces and forums.
Health Conditions
The Food and Drug Administration (FDA) has warned that deaths and overdoses have occurred in people using both the brand-name product Duragesic and generic transdermal fentanyl patches. The FDA also warned that children are at particular risk for accidental death from exposure. Sometimes, a person with opioid dependence may take fentanyl as a substitute for heroin.
Symptoms Of Fentanyl Addiction
Drugs may contain deadly levels of fentanyl, and you wouldn’t be able to see it, taste it, or smell it. It is nearly impossible to tell if drugs have been mixed with fentanyl unless you test your drugs with fentanyl test strips. Many fatal overdoses thought to be from heroin have been from fentanyl.

Health Products
Drug enforcers theorize that dyes may help drug traffickers avoid detection with the drugs. They speculate that it may also be a way to tempt teens and young adults to take them. The claim that some of the colors have a stronger effect than others is a myth. In its liquid form, IMF can be found in nasal sprays, eye drops, and dropped onto paper or small candies. A .gov website belongs to an official government organization in the United States. Fentanyl affects people differently, depending on an individual’s size and overall health condition.

The Rise And Concern Of Counterfeit Pills
Naloxone is used to reverse the life-threatening effects of an overdose. It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood. Your doctor may also prescribe you naloxone if you are living in a household where there are small children or someone who has abused street or prescription drugs. You should make sure that you and your family members, caregivers, or the people who spend time with you know how to tell recognize an overdose, how to use naloxone, and what to do until emergency medical help arrives. Your doctor or pharmacist will show you and your family members how to use the medication. Ask your pharmacist for the instructions or visit the manufacturer’s website to get the instructions.
- For example, the person may obtain it as powders or pills or add it to containers such as eyedroppers or nasal sprays.
- U-47,700 was offered for an average price of U.S.$100.3 per gram for retail listings and an average price of U.S.$19.7 per gram for wholesale listings.
- Bring this list with you each time you visit a doctor or if you are admitted to the hospital.
- Our study provides new insights into the role of the darknet in the availability of non-pharmaceutical fentanyl, fentanyl analogs and other novel synthetic opioids.
- Dark web drugs market operators and vendors are aware of the increased law enforcement scrutiny and seizure efforts that arise from stocking fentanyl – resulting in many banning them outright.
- Identification of new substances highlights the value of cryptomarket data for early warning systems of emerging substance use trends.

Some opioids come directly from the opium poppy plant, but manufacturers make fentanyl in a lab and reproduce the chemical structure. It’s hard to predict the amount of fentanyl that could kill someone. As little as 2 milligrams may be lethal depending on how big your body is, what your tolerance for opioids is, and your past usage of fentanyl. After a fentanyl treatment, you may have side effects that hinder your thinking and reactions or cause dizziness or drowsiness. Because of this, don’t drive or do activities that require you to be fully alert and awake after your treatment.
Fentanyl Analogs
During the study period, an average of 2.8 kg of fentanyl-type substances were listed for sale at each time point of data collection. In addition, there were an average of 2,495 non-pharmaceutical oxycodone pills pressed with fentanyl available for purchase at each time point when data were collected. The information about the amount of fentanyl added to these pills was specified only by one vendor, in a total of 7 listings (out of 123), and was equal to 150μg. According to the study, AlphaBay operated from 2014 to 2017 and was considered the largest dark web marketplace at the time with more than 200,000 users. To give you a better idea, a typical single pill of ibuprofen is two hundred milligrams.

Fentanyl is up to 100 times more potent than morphine and 50 times more potent than heroin. Medications are the standard treatment for fentanyl addiction.32,33 Several medications have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of opioid use disorder. Another medication, lofexidine, has been approved for treatment of withdrawal symptoms.34 See “Medications for Opioid Use Disorder” for more information. No, it is illegal to buy fentanyl from darknet markets or any other source without a prescription.
In fact, most fentanyl-related deaths are from fentanyl made in illegal laboratories. Fentanyl is heavily trafficked into the US from other countries and sold as pills or powders, and it has largely replaced heroin in the drug supply. In some cases, these illicit formulations of fentanyl are made to look like other prescription opioid tablets. In addition to receiving treatment for a substance use disorder, people who use illegal drugs can help prevent overdoses by using fentanyl test strips.
Although the clinical scenarios may vary among patients, one of the main concerns is the level of expression of OIRD. In such cases, oxygen administration and respiratory assistance are a priority. An opioid drug antagonist such as naloxone can help to correct OIRD symptoms. Thus, the therapeutic approach should continue until a normal respiratory rate coincides with appropriate oxygen saturation levels.
We also routinely track dark web markets for additional risk factors, such as the trade in fentanyl and firearms. Our Research and Investigations Team also focuses on identifying new ways vendors use to disguise the trade of such illicit goods. What makes darknet markets particularly concerning is the anonymity they offer to both buyers and sellers. Transactions are conducted using cryptocurrencies such as Bitcoin, making it difficult to trace the identities of those involved.